Sensitive

Lung adenocarcinoma

near HLA-DRB1 · rs2760995

Where this position leads

Condition: EGFR Mutation-Positive Lung Adenocarcinoma

rs2760995 Condition: EGFR Mutation-Positive Lung Adenocarcinoma EGFR Mutation-Positive Lung Adenoca… Condition rs2760995 rs2760995 near HLA-DRB1

What the study found

Who was studied 13,267 East Asian ancestry cases, 37,190 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 7.46 z score higher; p = 9 × 10−14.

Where it sits Chromosome 6, band 6p21.32 — between genes, 16.7 kb from HLA-DRB1.

What each result means

A/A Two copies of the version the research linked to Lung adenocarcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lung adenocarcinoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lung adenocarcinoma. This is the starting point the study compared everyone against.
Source

Questions about rs2760995

What is rs2760995?

rs2760995 is a single position in the genome, in or near the near HLA-DRB1 gene. Published research associates it with lung adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2760995 linked to?

On MyGeneLog this position is linked to EGFR Mutation-Positive Lung Adenocarcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs2760995 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2760995 come from?

GWAS Catalog, Journal of the National Cancer Institute 2026, PMID:41581221. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung adenocarcinoma (rs2760995). MyGeneLog™. https://www.mygenelog.com/variants/rs2760995

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