Standard
Cholesterol, total
TRPS1 · rs2737229
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Cholesterol, total — no copies of the reported risk allele.
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesterol, total.
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesterol, total compared to the general population.
Source
Biological, clinical and population relevance of 95 loci for blood lipids
Teslovich TM,
Musunuru K,
Smith AV,
Edmondson AC,
Stylianou IM,
Koseki M,
Pirruccello JP,
Ripatti S,
Chasman DI,
Willer CJ,
Johansen CT,
Fouchier SW
and 197 more — show all
Isaacs A,
Peloso GM,
Barbalic M,
Ricketts SL,
Bis JC,
Aulchenko YS,
Thorleifsson G,
Feitosa MF,
Chambers J,
Orho-Melander M,
Melander O,
Johnson T,
Li X,
Guo X,
Li M,
Shin Cho Y,
Jin Go M,
Jin Kim Y,
Lee JY,
Park T,
Kim K,
Sim X,
Twee-Hee Ong R,
Croteau-Chonka DC,
Lange LA,
Smith JD,
Song K,
Hua Zhao J,
Yuan X,
Luan J,
Lamina C,
Ziegler A,
Zhang W,
Zee RY,
Wright AF,
Witteman JC,
Wilson JF,
Willemsen G,
Wichmann HE,
Whitfield JB,
Waterworth DM,
Wareham NJ,
Waeber G,
Vollenweider P,
Voight BF,
Vitart V,
Uitterlinden AG,
Uda M,
Tuomilehto J,
Thompson JR,
Tanaka T,
Surakka I,
Stringham HM,
Spector TD,
Soranzo N,
Smit JH,
Sinisalo J,
Silander K,
Sijbrands EJ,
Scuteri A,
Scott J,
Schlessinger D,
Sanna S,
Salomaa V,
Saharinen J,
Sabatti C,
Ruokonen A,
Rudan I,
Rose LM,
Roberts R,
Rieder M,
Psaty BM,
Pramstaller PP,
Pichler I,
Perola M,
Penninx BW,
Pedersen NL,
Pattaro C,
Parker AN,
Pare G,
Oostra BA,
O'Donnell CJ,
Nieminen MS,
Nickerson DA,
Montgomery GW,
Meitinger T,
McPherson R,
McCarthy MI,
McArdle W,
Masson D,
Martin NG,
Marroni F,
Mangino M,
Magnusson PK,
Lucas G,
Luben R,
Loos RJ,
Lokki ML,
Lettre G,
Langenberg C,
Launer LJ,
Lakatta EG,
Laaksonen R,
Kyvik KO,
Kronenberg F,
König IR,
Khaw KT,
Kaprio J,
Kaplan LM,
Johansson A,
Jarvelin MR,
Janssens AC,
Ingelsson E,
Igl W,
Kees Hovingh G,
Hottenga JJ,
Hofman A,
Hicks AA,
Hengstenberg C,
Heid IM,
Hayward C,
Havulinna AS,
Hastie ND,
Harris TB,
Haritunians T,
Hall AS,
Gyllensten U,
Guiducci C,
Groop LC,
Gonzalez E,
Gieger C,
Freimer NB,
Ferrucci L,
Erdmann J,
Elliott P,
Ejebe KG,
Döring A,
Dominiczak AF,
Demissie S,
Deloukas P,
de Geus EJ,
de Faire U,
Crawford G,
Collins FS,
Chen YD,
Caulfield MJ,
Campbell H,
Burtt NP,
Bonnycastle LL,
Boomsma DI,
Boekholdt SM,
Bergman RN,
Barroso I,
Bandinelli S,
Ballantyne CM,
Assimes TL,
Quertermous T,
Altshuler D,
Seielstad M,
Wong TY,
Tai ES,
Feranil AB,
Kuzawa CW,
Adair LS,
Taylor HA Jr,
Borecki IB,
Gabriel SB,
Wilson JG,
Holm H,
Thorsteinsdottir U,
Gudnason V,
Krauss RM,
Mohlke KL,
Ordovas JM,
Munroe PB,
Kooner JS,
Tall AR,
Hegele RA,
Kastelein JJ,
Schadt EE,
Rotter JI,
Boerwinkle E,
Strachan DP,
Mooser V,
Stefansson K,
Reilly MP,
Samani NJ,
Schunkert H,
Cupples LA,
Sandhu MS,
Ridker PM,
Rader DJ,
van Duijn CM,
Peltonen L,
Abecasis GR,
Boehnke M,
Kathiresan S
Nature · 2010 · PMID 20686565 · open access
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2737229
What is rs2737229?
rs2737229 is a single position in the genome, in or near the TRPS1 gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs2737229?
Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2737229 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2737229 come from?
GWAS Catalog, Nature 2010, PMID:20686565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants