0 181312227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,331 African American or Afro-Caribbean cases, 113,628 African American or Afro-Caribbean controls, 2,525 Hispanic or Latin American cases, 54,902 Hispanic or Latin American controls, 292 East Asian ancestry cases, 6,302 East Asian ancestry controls, 31,321 European ancestry cases, 393,906 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.11 higher (95% confidence interval 0.085-0.134); p = 4 × 10−22.
How common The G allele had a frequency of about 80% in the people studied.
Where it sits Chromosome 19, band 19q13.41 — between genes, 1.7 kb from KLK6.
What each result means
A/ANo copy of the version the research linked to Erythematosquamous dermatosis (PheCode 690). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Erythematosquamous dermatosis (PheCode 690). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Erythematosquamous dermatosis (PheCode 690). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs268890
What is rs268890?
rs268890 is a single position in the genome, in or near the near KLK6 gene. Published research associates it with erythematosquamous dermatosis (phecode 690). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs268890 linked to?
On MyGeneLog this position is linked to Erythematosquamous Dermatosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs268890 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs268890 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 181312227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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