Sensitive

Inflammatory bowel disease

RABEP2 · rs26528

Where this position leads

Condition: Inflammatory Bowel Disease

rs26528 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs26528 rs26528 RABEP2

What the study found

Who was studied 12,924 European ancestry cases, 21,442 European ancestry controls; replicated in 25,683 European ancestry cases, 17,015 European ancestry controls.

The effect Each copy of the C allele carried 1.10 times the odds of Inflammatory bowel disease (95% confidence interval 1.067-1.13); p = 1 × 10−21.

How common The C allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 16, band 16p11.2 — in an intron of IL27.

What each result means

C/C Two copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs26528

What is rs26528?

rs26528 is a single position in the genome, in or near the RABEP2 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs26528 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs26528?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs26528 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs26528 come from?

GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inflammatory bowel disease (rs26528). MyGeneLog™. https://www.mygenelog.com/variants/rs26528

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