Standard

Metabolic traits

LEF1 · rs2650000

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Metabolic traits compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Metabolic traits.
C/C Published research associates this genotype with typical/baseline likelihood of Metabolic traits — no copies of the reported risk allele.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2650000

What is rs2650000?

rs2650000 is a single position in the genome, in or near the LEF1 gene. Published research associates it with metabolic traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs2650000?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), alcohol and the flush (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2650000 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2650000 come from?

GWAS Catalog, Nat Genet 2008, PMID:19060910. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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