4 5441136222231Reads by AI crawlersClaude4ChatGPT1Google · Gemini1Perplexity3Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others31Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,763 Northern Finnish founder individuals.
The effect
Each copy of the A allele shifted the measure 0.4 mmol/l lower (95% confidence interval 0.25-0.55); p = 3 × 10−11.
How common The A allele had a frequency of about 45% in the people studied.
Where it sits Chromosome 12, band 12q24.31 — in an intron of HNF1A-AS1.
What each result means
A/ATwo copies of the version the research linked to Metabolic traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Metabolic traits. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Metabolic traits. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2650000
What is rs2650000?
rs2650000 is a single position in the genome, in or near the LEF1 gene. Published research associates it with metabolic traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2650000 linked to?
On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs2650000?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), alcohol and the flush (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2650000 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2650000 come from?
GWAS Catalog, Nat Genet 2008, PMID:19060910. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 5441136222231Reads by AI crawlersClaude4ChatGPT1Google · Gemini1Perplexity3Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others31Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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