Sensitive

Type 2 diabetes

RPSAP52 · rs2583921

Where this position leads

Condition: Type 2 Diabetes

rs2583921 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs2583921 rs2583921 RPSAP52

What the study found

Who was studied 148,726 European ancestry cases, 965,732 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0954 higher (95% confidence interval 0.08-0.111); p = 9 × 10−33.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 12, band 12q14.3 — in an intron of RPSAP52.

What each result means

A/A No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2583921

What is rs2583921?

rs2583921 is a single position in the genome, in or near the RPSAP52 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2583921 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs2583921 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2583921 come from?

GWAS Catalog, Nature genetics 2020, PMID:32541925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs2583921). MyGeneLog™. https://www.mygenelog.com/variants/rs2583921

← See all variants