Sensitive

Substance use disorder

near LINC02829 · rs2523432

Where this position leads

Condition: Substance Use Disorder

rs2523432 Condition: Substance Use Disorder Substance Use Disorder Condition rs2523432 rs2523432 near LINC028…

What the study found

Who was studied 1,458,999 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 6.75 lower; p = 1 × 10−11.

Where it sits Chromosome 6, band 6p22.1 — between genes, 5.8 kb from LINC02829.

What each result means

A/A Two copies of the version the research linked to Substance use disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Substance use disorder. That is a smaller link than two copies.
G/G No copy of the version the research linked to Substance use disorder. This is the starting point the study compared everyone against.
Source

Questions about rs2523432

What is rs2523432?

rs2523432 is a single position in the genome, in or near the near LINC02829 gene. Published research associates it with substance use disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2523432 linked to?

On MyGeneLog this position is linked to Substance Use Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs2523432 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2523432 come from?

GWAS Catalog, Molecular psychiatry 2026, PMID:41057643. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Substance use disorder (rs2523432). MyGeneLog™. https://www.mygenelog.com/variants/rs2523432

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