Standard

Intelligence

DBN1 · rs2450333

Where this position leads

Condition: Intelligence

rs2450333 Condition: Intelligence Intelligence Condition rs2450333 rs2450333 DBN1

What the study found

Who was studied 269,867 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 6.73 z-score lower; p = 2 × 10−11.

Where it sits Chromosome 5, band 5q35.3 — in an intron of DBN1.

What each result means

A/A Two copies of the version the research linked to Intelligence. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Intelligence. That is a smaller link than two copies.
G/G No copy of the version the research linked to Intelligence. This is the starting point the study compared everyone against.
Source

Questions about rs2450333

What is rs2450333?

rs2450333 is a single position in the genome, in or near the DBN1 gene. Published research associates it with intelligence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2450333 linked to?

On MyGeneLog this position is linked to Intelligence. The research behind each link, and its sources, are set out on that condition page.

Does having rs2450333 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2450333 come from?

GWAS Catalog, Nature genetics 2018, PMID:29942086. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Intelligence (rs2450333). MyGeneLog™. https://www.mygenelog.com/variants/rs2450333

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