Sensitive

Systemic lupus erythematosus

MIR146A · rs2431697

Where this position leads

Condition: Systemic Lupus Erythematosus

rs2431697 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition Topic: Heart and circulation Heart and circulation Topic rs2431697 rs2431697 MIR146A

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2431697

What is rs2431697?

rs2431697 is a single position in the genome, in or near the MIR146A gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2431697 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2431697?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (6 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2431697 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2431697 come from?

GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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