Standard

High density lipoprotein cholesterol levels

CETP · rs2303790

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

Drug: Statins

rs2303790 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition Drug: Statins Statins Drug rs2303790 rs2303790 CETP

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of High density lipoprotein cholesterol levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with High density lipoprotein cholesterol levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of High density lipoprotein cholesterol levels compared to the general population.
Source

Questions about rs2303790

What is rs2303790?

rs2303790 is a single position in the genome, in or near the CETP gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2303790 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does rs2303790 affect how medicines work?

CETP carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs2303790 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2303790 come from?

GWAS Catalog, Sci Rep 2019, PMID:30718733. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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