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Who was studied 10,708 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.526 lower (95% confidence interval 0.47-0.58); p = 2 × 10−72.
How common The A allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.
What each result means
A/ATwo copies of the version the research linked to Protein Wnt-3a levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Protein Wnt-3a levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Protein Wnt-3a levels. This is the starting point the study compared everyone against.
rs2301519 is a single position in the genome, in or near the F5 gene. Published research associates it with protein wnt-3a levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs2301519 affect how medicines work?
F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs2301519 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2301519 come from?
GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1411219Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Protein Wnt-3a levels (rs2301519). MyGeneLog™. https://www.mygenelog.com/variants/rs2301519