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Height

CLMN · rs2282270

Where this position leads

Condition: Height

Drug: Statins

rs2282270 Condition: Height Height Condition Drug: Statins Statins Drug rs2282270 rs2282270 CLMN

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0156 lower (95% confidence interval 0.011-0.021); p = 2 × 10−9.

How common The C allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 14, band 14q32.13 — in an intron of CLMN.

What each result means

C/C Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source
Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures
Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P
Nature communications · 2025 · PMID 40436827 · open access

Questions about rs2282270

What is rs2282270?

rs2282270 is a single position in the genome, in or near the CLMN gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2282270 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does rs2282270 affect how medicines work?

CLMN carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs2282270 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2282270 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs2282270). MyGeneLog™. https://www.mygenelog.com/variants/rs2282270

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