A/APublished research associates this genotype with typical/baseline likelihood of Crohn's disease — no copies of the reported risk allele. (GWAS Catalog, Inflamm Bowel Dis 2015, PMID:25489960)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Crohn's disease. (GWAS Catalog, Inflamm Bowel Dis 2015, PMID:25489960)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Crohn's disease compared to the general population. (GWAS Catalog, Inflamm Bowel Dis 2015, PMID:25489960)
rs224143 is a single position in the genome, in or near the ZNF365 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs224143 linked to?
On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs224143 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs224143 come from?
GWAS Catalog, Inflamm Bowel Dis 2015, PMID:25489960. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.