3 5252137223225Reads by AI crawlersClaude5ChatGPT2Google · Gemini1Perplexity3Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total52Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 564 European ancestry cases, 1,776 European ancestry controls; replicated in 1,682 European ancestry cases, 3,926 European ancestry controls.
The effect
Each copy of the A allele carried 1.31 times the odds of Systemic sclerosis (95% confidence interval 1.15-1.43); p = 5 × 10−9.
How common The A allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 5, band 5q33.1 — in an intron of TNIP1.
What each result means
A/ATwo copies of the version the research linked to Systemic sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Systemic sclerosis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Systemic sclerosis. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2233287
What is rs2233287?
rs2233287 is a single position in the genome, in or near the TNIP1 gene. Published research associates it with systemic sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2233287 linked to?
On MyGeneLog this position is linked to Systemic Sclerosis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs2233287?
Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2233287 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2233287 come from?
GWAS Catalog, PLoS Genet 2011, PMID:21750679. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 5252137223225Reads by AI crawlersClaude5ChatGPT2Google · Gemini1Perplexity3Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total52Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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