F5 · rs2213867
Where this position leads
What the study found
Who was studied 10,708 European ancestry individuals.
The effect Each copy of the T allele shifted the measure 0.262 lower (95% confidence interval 0.23-0.29); p = 2 × 10−67.
How common The T allele had a frequency of about 73% in the people studied.
Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.
What ClinVar records
Classification
Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-11-11.
ClinVar record 1224783 NM_000130.5(F5):c.6193+173A>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs2213867 is a single position in the genome, in or near the F5 gene. Published research associates it with solute carrier family 22 member 16 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Solute carrier family 22 member 16 levels (rs2213867). MyGeneLog™. https://www.mygenelog.com/variants/rs2213867