Standard

C-reactive protein

IL6 · rs2097677

Where this position leads

Condition: C-Reactive Protein Levels

rs2097677 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs2097677 rs2097677 IL6

What the study found

Who was studied 10,112 Japanese ancestry individuals; replicated in 2,742 Japanese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.101 higher (95% confidence interval 0.07-0.13); p = 4 × 10−11.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 7, band 7p15.3 — inside STEAP1B.

What each result means

A/A Two copies of the version the research linked to C-reactive protein. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to C-reactive protein. That is a smaller link than two copies.
G/G No copy of the version the research linked to C-reactive protein. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2097677

What is rs2097677?

rs2097677 is a single position in the genome, in or near the IL6 gene. Published research associates it with c-reactive protein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2097677 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2097677?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), exercise and muscle (1 papers), brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2097677 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2097677 come from?

GWAS Catalog, Hum Mol Genet 2010, PMID:21196492. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C-reactive protein (rs2097677). MyGeneLog™. https://www.mygenelog.com/variants/rs2097677

← See all variants