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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.00177 lower (95% confidence interval 0.0012-0.0024); p = 8 × 10−9.
How common The G allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 4, band 4q23 — in an intron of MTTP.
What each result means
A/ANo copy of the version the research linked to Triglycerides in very small VLDL. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Triglycerides in very small VLDL. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Triglycerides in very small VLDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs2035816
What is rs2035816?
rs2035816 is a single position in the genome, in or near the MTTP gene. Published research associates it with triglycerides in very small vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2035816 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs2035816 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2035816 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Triglycerides in very small VLDL (rs2035816). MyGeneLog™. https://www.mygenelog.com/variants/rs2035816