2 503318223226Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others26Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 372 Japanese ancestry Crohn's disease cases, 372 Japanese ancestry ulcerative colitis cases; replicated in 607 Japanese ancestry Crohn's disease cases, 376 Japanese ancestry ulcerative colitis cases.
The effect
Each copy of the T allele carried 1.67 times the odds of Ulcerative colitis or Crohn's disease (95% confidence interval 1.47-1.92); p = 4 × 10−13.
How common The T allele had a frequency of about 47% in the people studied.
Where it sits Chromosome 9, band 9q32 — between genes, 15.1 kb from LOC645266.
What each result means
C/CNo copy of the version the research linked to Ulcerative colitis or Crohn's disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Ulcerative colitis or Crohn's disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Ulcerative colitis or Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs2006996 is a single position in the genome, in or near the TNFSF15 gene. Published research associates it with ulcerative colitis or crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2006996 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2006996 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2006996 come from?
GWAS Catalog, Gastroenterology 2011, PMID:21699788. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 503318223226Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others26Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Ulcerative colitis or Crohn's disease (rs2006996). MyGeneLog™. https://www.mygenelog.com/variants/rs2006996