C/CPublished research associates this genotype with typical/baseline likelihood of Ulcerative colitis or Crohn's disease — no copies of the reported risk allele. (GWAS Catalog, Gastroenterology 2011, PMID:21699788)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Ulcerative colitis or Crohn's disease. (GWAS Catalog, Gastroenterology 2011, PMID:21699788)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Ulcerative colitis or Crohn's disease compared to the general population. (GWAS Catalog, Gastroenterology 2011, PMID:21699788)
rs2006996 is a single position in the genome, in or near the TNFSF15 gene. Published research associates it with ulcerative colitis or crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2006996 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2006996 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2006996 come from?
GWAS Catalog, Gastroenterology 2011, PMID:21699788. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.