0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 536 African American or Afro-Caribbean cases, 120,708 African American or Afro-Caribbean controls, 2,468 European ancestry cases, 445,620 European ancestry controls, 278 Hispanic or Latin American cases, 59,249 Hispanic or Latin American controls.
The effect
Each copy of the C allele shifted the measure 2.81 lower (95% confidence interval 2.77-2.84); p = 3 × 10−11.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 11, band 11q12.2 — a missense change in DAGLA.
What each result means
C/CTwo copies of the version the research linked to Chondrocalcinosis (PheCode 274.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Chondrocalcinosis (PheCode 274.21). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Chondrocalcinosis (PheCode 274.21). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs200294323
What is rs200294323?
rs200294323 is a single position in the genome, in or near the DAGLA gene. Published research associates it with chondrocalcinosis (phecode 274.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs200294323 linked to?
On MyGeneLog this position is linked to Chondrocalcinosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs200294323 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs200294323 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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