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Calcium/calmodulin-dependent protein kinase type 1 levels

F5 · rs192253150

Where this position leads

Drug: Combined hormonal contraceptives

rs192253150 Drug: Combined hormonal contraceptives Combined hormonal contraceptives Drug rs192253150 rs192253150 F5

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.976 lower (95% confidence interval 0.76-1.19); p = 2 × 10−18.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.

What each result means

A/A Two copies of the version the research linked to Calcium/calmodulin-dependent protein kinase type 1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Calcium/calmodulin-dependent protein kinase type 1 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Calcium/calmodulin-dependent protein kinase type 1 levels. This is the starting point the study compared everyone against.
Source

Questions about rs192253150

What is rs192253150?

rs192253150 is a single position in the genome, in or near the F5 gene. Published research associates it with calcium/calmodulin-dependent protein kinase type 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs192253150 affect how medicines work?

F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs192253150 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs192253150 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Calcium/calmodulin-dependent protein kinase type 1 levels (rs192253150). MyGeneLog™. https://www.mygenelog.com/variants/rs192253150

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