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Monocyte count

APLF · rs190855339

Where this position leads

Condition: Monocyte Count

rs190855339 Condition: Monocyte Count Monocyte Count Condition rs190855339 rs190855339 APLF

What the study found

Who was studied 349,856 European ancestry individuals, 95,119 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.103 lower (95% confidence interval 0.076-0.131); p = 1 × 10−13.

Where it sits Chromosome 2, band 2p13.3 — in an intron of APLF.

What each result means

A/A No copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs190855339

What is rs190855339?

rs190855339 is a single position in the genome, in or near the APLF gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs190855339 linked to?

On MyGeneLog this position is linked to Monocyte Count. The research behind each link, and its sources, are set out on that condition page.

Does having rs190855339 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs190855339 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Monocyte count (rs190855339). MyGeneLog™. https://www.mygenelog.com/variants/rs190855339

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