3 5132139223224Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity3Meta AI9Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 6,968 European ancestry cases, 20,464 European ancestry controls; replicated in 10,679 European ancestry cases, 26,715 European ancestry controls, 397 Iranian ancestry cases, 342 Iranian ancestry controls, 1,239 Indian ancestry cases, 990 Indian ancestry controls, 1,134 East Asian ancestry cases, 3,719 East Asian ancestry controls.
The effect
Each copy of the G allele carried 1.13 times the odds of Ulcerative colitis (95% confidence interval 1.1-1.16); p = 3 × 10−13.
How common The G allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 18, band 18p11.21 — in an intron of PTPN2.
What each result means
A/ANo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1893217
What is rs1893217?
rs1893217 is a single position in the genome, in or near the PTPN2 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1893217 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs1893217?
Subjects that appear in the title or abstract of the same papers as this rsID include gut and food intolerance (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1893217 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1893217 come from?
GWAS Catalog, Nat Genet 2015, PMID:26192919. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 5132139223224Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity3Meta AI9Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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