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Meningitis

SCAPER · rs188530871

Where this position leads

What the study found

Who was studied 7 Vis (founder/genetic isolate) cases, 16 Korculan (founder/genetic isolate) cases, 7 Split cases, 953 Vis (founder/genetic isolate) controls, 2,682 Korculan (founder/genetic isolate) controls, 959 Split controls.

The effect Each copy of the T allele carried 1.08 times the odds of Meningitis (95% confidence interval 1.06-1.1); p = 8 × 10⁻¹¹.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 15, band 15q24.3 — in an intron of SCAPER.

What each result means

C/C No copy of the version the research linked to Meningitis. This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Meningitis. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Meningitis. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk

Gelemanović A, Ćatipović Ardalić T, Pribisalić A, Hayward C, Kolčić I, Polašek O

International journal of molecular sciences · 2023 · PMID 37108169 · open access

Questions about rs188530871

What is rs188530871?

rs188530871 is a single position in the genome, in or near the SCAPER gene. Published research associates it with meningitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs188530871 linked to?

On MyGeneLog this position is linked to Meningitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs188530871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs188530871 come from?

GWAS Catalog, International journal of molecular sciences 2023, PMID:37108169. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Meningitis (rs188530871). MyGeneLog™. https://www.mygenelog.com/variants/rs188530871

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