Standard

Triglycerides in chylomicrons and extremely large VLDL

SOD2 · rs184158723

Where this position leads

Condition: Age-Related Macular Degeneration

rs184158723 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs184158723 rs184158723 SOD2

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0165 lower (95% confidence interval 0.011-0.022); p = 3 × 10−9.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 6, band 6q25.3 — between genes, 57.7 kb from SOD2.

What each result means

A/A Two copies of the version the research linked to Triglycerides in chylomicrons and extremely large VLDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Triglycerides in chylomicrons and extremely large VLDL. That is a smaller link than two copies.
G/G No copy of the version the research linked to Triglycerides in chylomicrons and extremely large VLDL. This is the starting point the study compared everyone against.
Source

Questions about rs184158723

What is rs184158723?

rs184158723 is a single position in the genome, in or near the SOD2 gene. Published research associates it with triglycerides in chylomicrons and extremely large vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs184158723 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs184158723 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs184158723 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglycerides in chylomicrons and extremely large VLDL (rs184158723). MyGeneLog™. https://www.mygenelog.com/variants/rs184158723

← See all variants