Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio
PLCB1 · rs183719966
0 9225Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others5Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.889 higher (95% confidence interval 0.68-1.1); p = 7 × 10−17.
How common The G allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 20, band 20p12.3 — inside PLCB1.
What each result means
G/GTwo copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio. This is the starting point the study compared everyone against.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs183719966
What is rs183719966?
rs183719966 is a single position in the genome, in or near the PLCB1 gene. Published research associates it with free cholesterol to cholesteryl esters in very large hdl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs183719966 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs183719966 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs183719966 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 9225Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others5Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio (rs183719966). MyGeneLog™. https://www.mygenelog.com/variants/rs183719966