Standard

Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio

near LINC02026 · rs181016365

Where this position leads

Condition: Age-Related Macular Degeneration

rs181016365 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs181016365 rs181016365 near LINC020…

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.734 higher (95% confidence interval 0.53-0.94); p = 4 × 10−13.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 3, band 3q29 — between genes, 13.1 kb from LINC02026.

What each result means

C/C No copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs181016365

What is rs181016365?

rs181016365 is a single position in the genome, in or near the near LINC02026 gene. Published research associates it with free cholesterol to cholesteryl esters in very large hdl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs181016365 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs181016365 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs181016365 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Free Cholesterol to Cholesteryl Esters in Very Large HDL ratio (rs181016365). MyGeneLog™. https://www.mygenelog.com/variants/rs181016365

← See all variants