Who was studied 95,119 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0468 lower (95% confidence interval 0.037-0.056); p = 8 × 10−22.
How common The A allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 3, band 3p21.31 — a missense change in CCR2.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte count compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte count.
G/GPublished research associates this genotype with typical/baseline likelihood of Monocyte count — no copies of the reported risk allele.
rs1799864 is a single position in the genome, in or near the CCR2 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1799864 linked to?
On MyGeneLog this position is linked to Monocyte Count. The research behind each link, and its sources, are set out on that condition page.
Does having rs1799864 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1799864 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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