Sensitive

Renal cell carcinoma

KCNQ1 · rs179784

Where this position leads

Condition: Renal Cell Carcinoma

rs179784 Condition: Renal Cell Carcinoma Renal Cell Carcinoma Condition rs179784 rs179784 KCNQ1

What the study found

Who was studied 5,313 East Asian ancestry cases, 96,912 East Asian ancestry controls, 25,890 European ancestry cases, 743,585 European ancestry controls, 897 African American cases, 3,109 African American controls, 1,612 Hispanic or Latin American cases, 2,180 Hispanic or Latin American controls.

The effect Each copy of the A allele carried 0.91 times the odds of Renal cell carcinoma (95% confidence interval 0.89-0.93); p = 2 × 10−22.

How common The A allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 11, band 11p15.5 — in an intron of KCNQ1.

What each result means

A/A Two copies of the version the research linked to Renal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Renal cell carcinoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Renal cell carcinoma. This is the starting point the study compared everyone against.
Source

Questions about rs179784

What is rs179784?

rs179784 is a single position in the genome, in or near the KCNQ1 gene. Published research associates it with renal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs179784 linked to?

On MyGeneLog this position is linked to Renal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs179784 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs179784 come from?

GWAS Catalog, Nature communications 2026, PMID:42000752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Renal cell carcinoma (rs179784). MyGeneLog™. https://www.mygenelog.com/variants/rs179784

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