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Linoleic acid to total fatty acids percentage

near INCENP · rs1792909

Where this position leads

Condition: Age-Related Macular Degeneration

rs1792909 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs1792909 rs1792909 near INCENP

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0465 lower (95% confidence interval 0.031-0.062); p = 5 × 10−9.

How common The G allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 11, band 11q12.3 — between genes, 0.2 kb from EEF1DP8.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Linoleic acid to total fatty acids percentage — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Linoleic acid to total fatty acids percentage.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Linoleic acid to total fatty acids percentage compared to the general population.
Source

Questions about rs1792909

What is rs1792909?

rs1792909 is a single position in the genome, in or near the near INCENP gene. Published research associates it with linoleic acid to total fatty acids percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1792909 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs1792909 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1792909 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Linoleic acid to total fatty acids percentage (rs1792909). MyGeneLog™. https://www.mygenelog.com/variants/rs1792909

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