Gene Knowledge Graph
UTC
Sensitive

Multiple sclerosis

TAGAP · rs1738074

Where this position leads

Condition: Multiple Sclerosis

rs1738074 Condition: Multiple Sclerosis Multiple Sclerosis Condition Topic: Gut and food intolerance Gut and food intolerance Topic rs1738074 rs1738074 TAGAP

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Multiple sclerosis compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Multiple sclerosis.
T/T Published research associates this genotype with typical/baseline likelihood of Multiple sclerosis — no copies of the reported risk allele.
Source
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
International Multiple Sclerosis Genetics Consortium
Science (New York, N.Y.) · 2019 · PMID 31604244

What people read about alongside this

Gut and food intolerance5

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs1738074

What is rs1738074?

rs1738074 is a single position in the genome, in or near the TAGAP gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1738074 linked to?

On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs1738074?

Subjects that appear in the title or abstract of the same papers as this rsID include gut and food intolerance (5 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs1738074 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1738074 come from?

GWAS Catalog, Science 2019, PMID:31604244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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