C/CPublished research associates this genotype with typical/baseline likelihood of Crohn's disease — no copies of the reported risk allele. (GWAS Catalog, Nature 2007, PMID:17554300)
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Crohn's disease. (GWAS Catalog, Nature 2007, PMID:17554300)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Crohn's disease compared to the general population. (GWAS Catalog, Nature 2007, PMID:17554300)
Source: GWAS Catalog, Nature 2007, PMID:17554300
Questions about rs17221417
What is rs17221417?
rs17221417 is a single position in the genome, in or near the NOD2 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17221417 linked to?
On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs17221417 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17221417 come from?
GWAS Catalog, Nature 2007, PMID:17554300. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.