2 4532138123220Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity3Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others20Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,748 European ancestry cases, 2,938 European ancestry controls; replicated in (see Parkes 2007).
The effect
Each copy of the G allele carried 1.29 times the odds of Crohn's disease (95% confidence interval 1.13-1.46); p = 4 × 10−11.
How common The G allele had a frequency of about 29% in the people studied.
Where it sits Chromosome 16, band 16q12.1 — in an intron of NOD2.
What each result means
C/CNo copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs17221417 is a single position in the genome, in or near the NOD2 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17221417 linked to?
On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs17221417 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17221417 come from?
GWAS Catalog, Nature 2007, PMID:17554300. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4532138123220Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity3Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others20Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.