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Menstruation quality of life impact (fever)

OPRM1 · rs17181171

Where this position leads

What the study found

Who was studied 112 Japanese ancestry female cases, 5,622 Japanese ancestry female controls; replicated in 157 Japanese ancestry female cases, 5,457 Japanese ancestry female controls.

The effect Each copy of the A allele shifted the measure 1.02 higher (95% confidence interval 0.67-1.38); p = 2 × 10⁻⁸.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 6, band 6q25.2 — in an intron of OPRM1.

What each result means

A/A Two copies of the version the research linked to Menstruation quality of life impact (fever). That is the strongest link of the three results. A link in a study is not a diagnosis.

A/G One copy of the version the research linked to Menstruation quality of life impact (fever). That is a smaller link than two copies.

G/G No copy of the version the research linked to Menstruation quality of life impact (fever). This is the starting point the study compared everyone against.

Source

Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs

Hirata T, Koga K, Johnson TA, Morino R, Nakazono K, Kamitsuji S, Akita M, Kawajiri M, Kami A, Hoshi Y, Tada A, Ishikawa K

and 6 more — show all

Hine M, Kobayashi M, Kurume N, Fujii T, Kamatani N, Osuga Y

Scientific reports · 2018 · PMID 29855537 · open access

Questions about rs17181171

What is rs17181171?

rs17181171 is a single position in the genome, in or near the OPRM1 gene. Published research associates it with menstruation quality of life impact (fever). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs17181171 affect how medicines work?

OPRM1 carries pharmacogenomic findings for Opioids. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs17181171 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17181171 come from?

GWAS Catalog, Sci Rep 2018, PMID:29855537. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Menstruation quality of life impact (fever) (rs17181171). MyGeneLog™. https://www.mygenelog.com/variants/rs17181171

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