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Intraocular pressure

COL24A1 · rs17129031

Where this position leads

Condition: Glaucoma

rs17129031 Condition: Glaucoma Glaucoma Condition rs17129031 rs17129031 COL24A1

What the study found

Who was studied 115,486 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.153 lower (95% confidence interval 0.1-0.2); p = 1 × 10−8.

How common The T allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 1, band 1p22.3 — inside LINC02795.

What each result means

C/C No copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17129031

What is rs17129031?

rs17129031 is a single position in the genome, in or near the COL24A1 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17129031 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs17129031 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17129031 come from?

GWAS Catalog, Hum Mol Genet 2018, PMID:29617998. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intraocular pressure (rs17129031). MyGeneLog™. https://www.mygenelog.com/variants/rs17129031

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