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Who was studied 374,971 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 6.5 z score higher; p = 8 × 10−11.
How common The A allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 3, band 3p12.2 — in an intron of LINC02027.
What each result means
A/ATwo copies of the version the research linked to Feeling fed-up. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Feeling fed-up. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Feeling fed-up. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 29500382 · open access
Questions about rs17018482
What is rs17018482?
rs17018482 is a single position in the genome, in or near the LINC02027 gene. Published research associates it with feeling fed-up. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17018482 linked to?
On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.
Does having rs17018482 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17018482 come from?
GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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