Standard

Diastolic blood pressure

PHB · rs16948048

Where this position leads

Condition: Blood Pressure

rs16948048 Condition: Blood Pressure Blood Pressure Condition rs16948048 rs16948048 PHB

What the study found

Who was studied 34,433 European ancestry individuals; replicated in Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.31 mm Hg higher (95% confidence interval 0.21-0.41); p = 5 × 10−9.

How common The G allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 17, band 17q21.33 — inside ZNF652-AS1.

What each result means

A/A No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs16948048

What is rs16948048?

rs16948048 is a single position in the genome, in or near the PHB gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16948048 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs16948048?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs16948048 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16948048 come from?

GWAS Catalog, Nat Genet 2009, PMID:19430483. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs16948048). MyGeneLog™. https://www.mygenelog.com/variants/rs16948048

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