7 1411228Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple2Others8Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 144,737 African ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.038 SD unit higher (95% confidence interval 0.025-0.051); p = 3 × 10−8.
How common The T allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 16, band 16p13.13 — inside RMI2.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Refractive error — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Refractive error.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Refractive error compared to the general population.
Nature genetics · 2026 · PMID 42009823 · open access
Questions about rs1646026
What is rs1646026?
rs1646026 is a single position in the genome, in or near the RMI2 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1646026 linked to?
On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.
Does having rs1646026 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1646026 come from?
GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
7 1411228Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple2Others8Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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