1 2511422213Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others13Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 10,411 European ancestry cases, 474,568 European ancestry controls, 8,448 East Asian ancestry cases, 168,903 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.12 lower (95% confidence interval 0.095-0.145); p = 5 × 10−21.
Where it sits Chromosome 15, band 15q24.1 — in an intron of LOXL1.
What each result means
C/CNo copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs1550437 is a single position in the genome, in or near the LOXL1 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1550437 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs1550437 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1550437 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2511422213Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others13Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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