Standard

Urate levels (UKB data field 30880)

ABCG2 · rs151297142

Where this position leads

Condition: Celiac Disease

Drug: Statins

rs151297142 Condition: Celiac Disease Celiac Disease Condition Drug: Statins Statins Drug rs151297142 rs151297142 ABCG2

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0426 lower (95% confidence interval 0.03-0.055); p = 4 × 10−12.

How common The T allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 4, band 4q22.1 — inside ABCG2.

What each result means

G/G No copy of the version the research linked to Urate levels (UKB data field 30880). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Urate levels (UKB data field 30880). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urate levels (UKB data field 30880). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs151297142

What is rs151297142?

rs151297142 is a single position in the genome, in or near the ABCG2 gene. Published research associates it with urate levels (ukb data field 30880). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs151297142 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does rs151297142 affect how medicines work?

ABCG2 carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs151297142 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs151297142 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urate levels (UKB data field 30880) (rs151297142). MyGeneLog™. https://www.mygenelog.com/variants/rs151297142

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