0 1511238Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,495,159 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0107 SD unit higher (95% confidence interval 0.0077-0.0136); p = 1 × 10−12.
How common The T allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 1, band 1q43 — between genes, 16 kb from MTND5P18.
What each result means
C/CNo copy of the version the research linked to Refractive error. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Refractive error. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Refractive error. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2026 · PMID 42009823 · open access
Questions about rs1490276
What is rs1490276?
rs1490276 is a single position in the genome, in or near the near ZP4 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1490276 linked to?
On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.
Does having rs1490276 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1490276 come from?
GWAS Catalog, Nature genetics 2026, PMID:42009823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1511238Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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