Standard

Glaucoma

near MTCYBP45 · rs149002763

Where this position leads

Condition: Glaucoma

rs149002763 Condition: Glaucoma Glaucoma Condition rs149002763 rs149002763 near MTCYBP45

What the study found

Who was studied 10,411 European ancestry cases, 474,568 European ancestry controls, 8,448 East Asian ancestry cases, 168,903 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.332 lower (95% confidence interval 0.23-0.43); p = 1 × 10−10.

Where it sits Chromosome 1, band 1p36.22 — between genes, 25.3 kb from MTCYBP45.

What each result means

C/C No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs149002763

What is rs149002763?

rs149002763 is a single position in the genome, in or near the near MTCYBP45 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs149002763 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs149002763 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149002763 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs149002763). MyGeneLog™. https://www.mygenelog.com/variants/rs149002763

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