Standard

Hay fever and/or eczema

near LINC02676 · rs1444789

Where this position leads

Condition: Hay Fever And/or Eczema

rs1444789 Condition: Hay Fever And/or Eczema Hay Fever And/or Eczema Condition rs1444789 rs1444789 near LINC026…

What the study found

Who was studied 84,034 European ancestry cases, 239,773 European ancestry controls.

The effect Each copy of the C allele carried 1.08 times the odds of Hay fever and/or eczema (95% confidence interval 1.06-1.091); p = 7 × 10−22.

How common The C allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 10, band 10p14 — between genes, 47.8 kb from LINC02676.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hay fever and/or eczema compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hay fever and/or eczema.
T/T Published research associates this genotype with typical/baseline likelihood of Hay fever and/or eczema — no copies of the reported risk allele.
Source

Questions about rs1444789

What is rs1444789?

rs1444789 is a single position in the genome, in or near the near LINC02676 gene. Published research associates it with hay fever and/or eczema. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1444789 linked to?

On MyGeneLog this position is linked to Hay Fever And/or Eczema. The research behind each link, and its sources, are set out on that condition page.

Does having rs1444789 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1444789 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31361310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hay fever and/or eczema (rs1444789). MyGeneLog™. https://www.mygenelog.com/variants/rs1444789

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