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Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio

near LINC02627 · rs144001648

Where this position leads

Condition: Age-Related Macular Degeneration

rs144001648 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs144001648 rs144001648 near LINC026…

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.238 higher (95% confidence interval 0.17-0.3); p = 1 × 10−12.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 10, band 10q25.1 — between genes, 96.3 kb from LINC02627.

What each result means

A/A No copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs144001648

What is rs144001648?

rs144001648 is a single position in the genome, in or near the near LINC02627 gene. Published research associates it with free cholesterol to cholesteryl esters in medium vldl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs144001648 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs144001648 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs144001648 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio (rs144001648). MyGeneLog™. https://www.mygenelog.com/variants/rs144001648

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