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Who was studied 412 African American or Afro-Caribbean cases, 104,388 African American or Afro-Caribbean controls, 2,512 European ancestry cases, 413,591 European ancestry controls, 275 Hispanic or Latin American cases, 53,398 Hispanic or Latin American controls.
The effect
Each copy of the T allele shifted the measure 2.39 lower (95% confidence interval 2.35-2.44); p = 4 × 10−13.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 6, band 6q21 — between genes, 44.5 kb from LINC02836.
What each result means
C/CNo copy of the version the research linked to Peyronie's disease (PheCode 604.3). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Peyronie's disease (PheCode 604.3). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Peyronie's disease (PheCode 604.3). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs143888834
What is rs143888834?
rs143888834 is a single position in the genome, in or near the near LINC02836 gene. Published research associates it with peyronie's disease (phecode 604.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs143888834 linked to?
On MyGeneLog this position is linked to Peyronie's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs143888834 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs143888834 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1714822Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot8Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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