0 1842219Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 58,370 mixed American ancestry individuals.
The effect
Each copy of the T allele shifted the measure 6.86 lower; p = 7 × 10−12.
Where it sits Chromosome 4, band 4q23 — in an intron of ADH1C.
What each result means
C/CNo copy of the version the research linked to Substance use disorder. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Substance use disorder. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Substance use disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Molecular psychiatry · 2026 · PMID 41057643 · open access
Questions about rs141973904
What is rs141973904?
rs141973904 is a single position in the genome, in or near the ADH1C gene. Published research associates it with substance use disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs141973904 linked to?
On MyGeneLog this position is linked to Substance Use Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs141973904 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs141973904 come from?
GWAS Catalog, Molecular psychiatry 2026, PMID:41057643. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1842219Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Substance use disorder (rs141973904). MyGeneLog™. https://www.mygenelog.com/variants/rs141973904