Free Cholesterol to Cholesteryl Esters in Large HDL ratio
LINC01692 · rs141520049
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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0386 higher (95% confidence interval 0.028-0.049); p = 4 × 10−13.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 21, band 21q21.2 — in an intron of LINC01692.
What each result means
A/ATwo copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Large HDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Large HDL ratio. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Large HDL ratio. This is the starting point the study compared everyone against.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs141520049
What is rs141520049?
rs141520049 is a single position in the genome, in or near the LINC01692 gene. Published research associates it with free cholesterol to cholesteryl esters in large hdl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs141520049 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs141520049 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs141520049 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Free Cholesterol to Cholesteryl Esters in Large HDL ratio (rs141520049). MyGeneLog™. https://www.mygenelog.com/variants/rs141520049