A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Renal cell carcinoma compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Renal cell carcinoma.
G/GPublished research associates this genotype with typical/baseline likelihood of Renal cell carcinoma — no copies of the reported risk allele.
Nature communications · 2026 · PMID 42000752 · open access
Questions about rs139729777
What is rs139729777?
rs139729777 is a single position in the genome, in or near the FANCD2 gene. Published research associates it with renal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs139729777 linked to?
On MyGeneLog this position is linked to Renal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs139729777 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs139729777 come from?
GWAS Catalog, Nature communications 2026, PMID:42000752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.