Sensitive

Hodgkin's disease (PheCode 201)

LINC02737 · rs138809598

Where this position leads

Condition: Hodgkin's Disease

rs138809598 Condition: Hodgkin's Disease Hodgkin's Disease Condition rs138809598 rs138809598 LINC02737

What the study found

Who was studied 215 African American or Afro-Caribbean cases, 121,633 African American or Afro-Caribbean controls, 975 European ancestry cases, 449,793 European ancestry controls.

The effect Each copy of the G allele shifted the measure 1.67 lower (95% confidence interval 1.6-1.73); p = 7 × 10−13.

How common The G allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 11, band 11q21 — in an intron of LINC02737.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Hodgkin's disease (PheCode 201) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hodgkin's disease (PheCode 201).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hodgkin's disease (PheCode 201) compared to the general population.
Source

Questions about rs138809598

What is rs138809598?

rs138809598 is a single position in the genome, in or near the LINC02737 gene. Published research associates it with hodgkin's disease (phecode 201). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs138809598 linked to?

On MyGeneLog this position is linked to Hodgkin's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs138809598 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138809598 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hodgkin's disease (PheCode 201) (rs138809598). MyGeneLog™. https://www.mygenelog.com/variants/rs138809598

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