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Hyperuricemia in high cholesterol intake

ABCG2 · rs138409370

Where this position leads

Drug: Statins

rs138409370 Drug: Statins Statins Drug rs138409370 rs138409370 ABCG2

What the study found

Who was studied 5,625 Korean ancestry individuals.

The effect Each copy of the T allele carried 1.63 times the odds of Hyperuricemia in high cholesterol intake (95% confidence interval 1.38-1.92); p = 1 × 10−8.

Where it sits Chromosome 4, band 4q22.1 — in an intron of ABCG2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Hyperuricemia in high cholesterol intake — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hyperuricemia in high cholesterol intake.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hyperuricemia in high cholesterol intake compared to the general population.
Source

Questions about rs138409370

What is rs138409370?

rs138409370 is a single position in the genome, in or near the ABCG2 gene. Published research associates it with hyperuricemia in high cholesterol intake. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs138409370 affect how medicines work?

ABCG2 carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs138409370 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138409370 come from?

GWAS Catalog, Scientific reports 2025, PMID:40835619. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hyperuricemia in high cholesterol intake (rs138409370). MyGeneLog™. https://www.mygenelog.com/variants/rs138409370

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