Standard

Urate levels

ABCG2 · rs13152371

Where this position leads

Drug: Statins

rs13152371 Drug: Statins Statins Drug rs13152371 rs13152371 ABCG2

What the study found

Who was studied 342,087 European ancestry individuals, 6,011 African ancestry individuals, 7,328 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0201 lower (95% confidence interval 0.015-0.025); p = 2 × 10−13.

Where it sits Chromosome 4, band 4q22.1 — inside ABCG2.

What each result means

C/C Two copies of the version the research linked to Urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Urate levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Urate levels. This is the starting point the study compared everyone against.
Source

Questions about rs13152371

What is rs13152371?

rs13152371 is a single position in the genome, in or near the ABCG2 gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs13152371 affect how medicines work?

ABCG2 carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs13152371 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13152371 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urate levels (rs13152371). MyGeneLog™. https://www.mygenelog.com/variants/rs13152371

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