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Monocyte count

RREB1 · rs1285885

Where this position leads

Conditions: Monocyte Count, Blood Cell Counts

rs1285885 Condition: Monocyte Count Monocyte Count Condition Condition: Blood Cell Counts Blood Cell Counts Condition rs1285885 rs1285885 RREB1

What the study found

Who was studied 639,696 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 5 × 10−42.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 6, band 6p24.3 — in an intron of RREB1.

What each result means

A/A Two copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
G/G No copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
Source

Questions about rs1285885

What is rs1285885?

rs1285885 is a single position in the genome, in or near the RREB1 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1285885 linked to?

On MyGeneLog this position is linked to Monocyte Count, Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs1285885 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1285885 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte count (rs1285885). MyGeneLog™. https://www.mygenelog.com/variants/rs1285885

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